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Advances in Neonatal Care: From NEC Prevention to Brain Injury Biomarkers

Pediatric Frontiers: Weekly Insights

Pediatria

Advances in Neonatal Care: From NEC Prevention to Brain Injury Biomarkers

This episode covers groundbreaking neonatal research including NEC prevention strategies, brain injury biomarkers, GVHD prophylaxis advances, and the impact of medical supply shortages on diagnostics.

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Bibliografia

1. Necrotizing enterocolitis: current understanding of the prevention and management.
Authors: Hu X, Liang H, Li F, et al.
Journal: Pediatric surgery international, 2024 Jan 10
PMID: 38196049
DOI: 10.1007/s00383-023-05619-3


2. Clinical Impact of the PDA and Its Management on Outcomes of Preterm Infants with NEC: A Review.
Authors: Gunasekaran V, Rodriguez RJ, Porcelli P, et al.
Journal: American journal of perinatology, 2026 Apr
PMID: 40829654
DOI: 10.1055/a-2685-2169


3. Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia.
Authors: Maude SL, Laetsch TW, Buechner J, et al.
Journal: The New England journal of medicine, 2018 Feb 1
PMID: 29385370
DOI: 10.1056/NEJMoa1709866


4. Introduction to neonatologist-performed echocardiography.
Authors: Groves AM, Singh Y, Dempsey E, et al.
Journal: Pediatric research, 2018 Jul
PMID: 30072808
DOI: 10.1038/s41390-018-0076-y


5. Glycemic variability and reference percentiles in very low birth weight preterm infants using continuous glucose monitoring.
Authors: Gutiérrez-Rosa I, Lubián-Gutiérrez M, Rodríguez-Barrios C, et al.
Journal: PloS one, 2026
PMID: 41894434
DOI: 10.1371/journal.pone.0341593


6. Epigenetic modifications of VEGF, cerebral hypoxia, and impaired cerebrovascular autoregulation as early indicators for preterm brain injury.
Authors: Brunsch CL, Klerk DH, Blommaert D, et al.
Journal: Function (Oxford, England), 2026 Apr 1
PMID: 41686493
DOI: 10.1152/function.088.2025


7. Diagnostic disruption during a blood culture bottle shortage: clinical and laboratory adaptation strategies.
Authors: Bansal H, Gupta A, Sinha KK, et al.
Journal: Microbiology spectrum, 2026 Apr 7
PMID: 41757894
DOI: 10.1128/spectrum.01646-25


8. Post-Transplantation Cyclophosphamide-Based Graft-versus-Host Disease Prophylaxis.
Authors: Bolaños-Meade J, Hamadani M, Wu J, et al.
Journal: The New England journal of medicine, 2023 Jun 22
PMID: 37342922
DOI: 10.1056/NEJMoa2215943


9. Association Between Rapid Progression, Early Mortality, and Imaging in Neonatal-Onset Alexander Disease.
Authors: Schwarz S, Steggerda SJ, de Vries LS, et al.
Journal: Neuropediatrics, 2026 Apr
PMID: 41443241
DOI: 10.1055/a-2773-9382


10. Diagnostic accuracy of the Picterus jaundice Pro app for neonatal jaundice: a single-center study from Turkiye.
Authors: Gülcan Kersin S, Ünal İ, Toprak Sevinç S, et al.
Journal: Scientific reports, 2026 Mar 19
PMID: 41857341
DOI: 10.1038/s41598-026-44927-1

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