Inside Nephrology: A Weekly Review
Nefrologia
Advances in Nephrology: From Nanotechnology to Precision Medicine
This week we explore groundbreaking nephrology research, from nanomaterial drug delivery systems to precision medicine approaches for kidney disease. We discuss advances in polycystic kidney disease management, novel findings about SGLT2 inhibitors and GLP-1 receptor agonists, and innovative predictive models for acute kidney injury.
Bibliography
1. Nanomaterial-Based Precision Drug Delivery for Advanced Nephrology Therapy: A Systematic Review.
Authors: Feng J, Zhang R, Chen X, et al.
Journal: International journal of nanomedicine, 2026
PMID: 41918846
DOI: 10.2147/IJN.S583744
2. Autosomal dominant polycystic kidney disease.
Authors: Ong ACM, Carriazo S, Ma BM, et al.
Journal: Lancet (London, England), 2026 Mar 28
PMID: 41771281
DOI: 10.1016/S0140-6736(26)00046-2
3. RESECT: A Randomised Controlled Trial of Audit and Feedback in Non-muscle-invasive Bladder Cancer Surgery.
Authors: Gallagher K, MacLennan S, Bhatt N, et al.
Journal: European urology, 2026 Apr
PMID: 41444076
DOI: 10.1016/j.eururo.2025.09.4174
4. Effects of Empagliflozin on Urine Biomarkers in EMPA-KIDNEY.
Authors: Malijan GB, Sardell RJ, Staplin N, et al.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation, 2026 Apr
PMID: 41177216
DOI: 10.1053/j.ajkd.2025.10.004
5. Diabetic kidney disease, biomarkers, and finerenone.
Authors: Verma A, Upadhyay A
Journal: Diabetes, obesity & metabolism, 2026 Apr
PMID: 41555617
DOI: 10.1111/dom.70464
6. Urinary tract infections in pregnancy.
Authors: Ansaldi Y, Martinez de Tejada Weber B
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2023 Oct
PMID: 36031053
DOI: 10.1016/j.cmi.2022.08.015
7. The effect of GLP-1 receptor agonists on renal outcomes: a systematic review and meta-analysis.
Authors: Sasaki T, Giang SM, Wu J, et al.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2026 Mar 31
PMID: 40982219
DOI: 10.1093/ndt/gfaf193
8. Antiproteinuric effect of SGLT2 inhibitors in non-diabetic glomerulopathies is dependent on body mass index.
Authors: Vargas-Brochero MJ, Russo I, Mazzierli T, et al.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2026 Mar 31
PMID: 40996459
DOI: 10.1093/ndt/gfaf197
9. Molecular Mechanisms of APOL1-Associated Kidney Disease.
Authors: Delrue C, Speeckaert R, Speeckaert MM
Journal: International journal of molecular sciences, 2026 Mar 21
PMID: 41898722
DOI: 10.3390/ijms27062863
10. MedFusion-gP-AKI: development and multicenter validation of a machine learning fusion model for early prediction of KDIGO stage 3 acute kidney injury in critically ill traumatic cervicothoracic spinal cord injury patients.
Authors: Wang Y, Wang J, Li W, et al.
Journal: Renal failure, 2026 Dec
PMID: 41803650
DOI: 10.1080/0886022X.2026.2640690
Authors: Feng J, Zhang R, Chen X, et al.
Journal: International journal of nanomedicine, 2026
PMID: 41918846
DOI: 10.2147/IJN.S583744
2. Autosomal dominant polycystic kidney disease.
Authors: Ong ACM, Carriazo S, Ma BM, et al.
Journal: Lancet (London, England), 2026 Mar 28
PMID: 41771281
DOI: 10.1016/S0140-6736(26)00046-2
3. RESECT: A Randomised Controlled Trial of Audit and Feedback in Non-muscle-invasive Bladder Cancer Surgery.
Authors: Gallagher K, MacLennan S, Bhatt N, et al.
Journal: European urology, 2026 Apr
PMID: 41444076
DOI: 10.1016/j.eururo.2025.09.4174
4. Effects of Empagliflozin on Urine Biomarkers in EMPA-KIDNEY.
Authors: Malijan GB, Sardell RJ, Staplin N, et al.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation, 2026 Apr
PMID: 41177216
DOI: 10.1053/j.ajkd.2025.10.004
5. Diabetic kidney disease, biomarkers, and finerenone.
Authors: Verma A, Upadhyay A
Journal: Diabetes, obesity & metabolism, 2026 Apr
PMID: 41555617
DOI: 10.1111/dom.70464
6. Urinary tract infections in pregnancy.
Authors: Ansaldi Y, Martinez de Tejada Weber B
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2023 Oct
PMID: 36031053
DOI: 10.1016/j.cmi.2022.08.015
7. The effect of GLP-1 receptor agonists on renal outcomes: a systematic review and meta-analysis.
Authors: Sasaki T, Giang SM, Wu J, et al.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2026 Mar 31
PMID: 40982219
DOI: 10.1093/ndt/gfaf193
8. Antiproteinuric effect of SGLT2 inhibitors in non-diabetic glomerulopathies is dependent on body mass index.
Authors: Vargas-Brochero MJ, Russo I, Mazzierli T, et al.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2026 Mar 31
PMID: 40996459
DOI: 10.1093/ndt/gfaf197
9. Molecular Mechanisms of APOL1-Associated Kidney Disease.
Authors: Delrue C, Speeckaert R, Speeckaert MM
Journal: International journal of molecular sciences, 2026 Mar 21
PMID: 41898722
DOI: 10.3390/ijms27062863
10. MedFusion-gP-AKI: development and multicenter validation of a machine learning fusion model for early prediction of KDIGO stage 3 acute kidney injury in critically ill traumatic cervicothoracic spinal cord injury patients.
Authors: Wang Y, Wang J, Li W, et al.
Journal: Renal failure, 2026 Dec
PMID: 41803650
DOI: 10.1080/0886022X.2026.2640690
