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Advances in Gynecologic Oncology and Reproductive Health

Advancements in Gynecology: A Weekly Review

Ginecologia e Ostetricia

Advances in Gynecologic Oncology and Reproductive Health

This week's episode covers advances in gynecologic oncology including cervical cancer staging and treatment, uterine fibroid management, endometriosis diagnostics, and HPV vaccination strategies. We also discuss pregnancy-related conditions including hypertensive disorders and gestational diabetes.

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Bibliography

1. The false-negative rate of sentinel lymph node biopsy and its related factors in early-stage cervical cancer: a systematic review and meta-analysis.
Authors: He C, Li F, He M, et al.
Journal: Acta oncologica (Stockholm, Sweden), 2026 Mar 16
PMID: 41837848
DOI: 10.2340/1651-226X.2026.44984


2. Treatment of Uterine Fibroid Symptoms with Relugolix Combination Therapy.
Authors: Al-Hendy A, Lukes AS, Poindexter AN 3rd, et al.
Journal: The New England journal of medicine, 2021 Feb 18
PMID: 33596357
DOI: 10.1056/NEJMoa2008283


3. Systematic approach to sonographic evaluation of the pelvis in women with suspected endometriosis, including terms, definitions and measurements: a consensus opinion from the International Deep Endometriosis Analysis (IDEA) group.
Authors: Guerriero S, Condous G, van den Bosch T, et al.
Journal: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2016 Sep
PMID: 27349699
DOI: 10.1002/uog.15955


4. Oral antihypertensive treatment during pregnancy: a systematic review and network meta-analysis.
Authors: Hup RJ, Damen JAA, Terstappen J, et al.
Journal: American journal of obstetrics and gynecology, 2025 Oct
PMID: 40216176
DOI: 10.1016/j.ajog.2025.04.011


5. Diagnosis and treatment of müllerian malformations.
Authors: Passos IMPE, Britto RL
Journal: Taiwanese journal of obstetrics & gynecology, 2020 Mar
PMID: 32127135
DOI: 10.1016/j.tjog.2020.01.003


6. Induction chemotherapy followed by standard chemoradiotherapy versus standard chemoradiotherapy alone in patients with locally advanced cervical cancer (GCIG INTERLACE): an international, multicentre, randomised phase 3 trial.
Authors: McCormack M, Eminowicz G, Gallardo D, et al.
Journal: Lancet (London, England), 2024 Oct 19
PMID: 39419054
DOI: 10.1016/S0140-6736(24)01438-7


7. Early Metformin in Gestational Diabetes: A Randomized Clinical Trial.
Authors: Dunne F, Newman C, Alvarez-Iglesias A, et al.
Journal: JAMA, 2023 Oct 24
PMID: 37786390
DOI: 10.1001/jama.2023.19869


8. Effect of physical activity and exercise on endometriosis-associated symptoms: a systematic review.
Authors: Tennfjord MK, Gabrielsen R, Tellum T
Journal: BMC women's health, 2021 Oct 9
PMID: 34627209
DOI: 10.1186/s12905-021-01500-4


9. High-Frequency Oscillation vs Mechanical Ventilation for Neonatal Acute Respiratory Distress Syndrome: A Randomized Clinical Trial.
Authors: Li J, Liu K, Yang Q, et al.
Journal: JAMA network open, 2026 Mar 2
PMID: 41801204
DOI: 10.1001/jamanetworkopen.2026.0268


10. Recent Developments in Human Papillomavirus (HPV) Vaccinology.
Authors: Williamson AL
Journal: Viruses, 2023 Jun 26
PMID: 37515128
DOI: 10.3390/v15071440

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