Advancements in Gastroenterology: A Weekly Review
Gastroenterologia
Advances in Gastroenterology: From Cholestasis to Crohns Disease
This week we cover Spanish guidelines for cholestatic liver diseases, location-specific Crohn's treatments, advances in MASLD therapy, and breakthroughs in eosinophilic esophagitis management. Plus updates on portal hypertension, autoimmune pancreatitis complications, and HCV treatment.
Bibliography
1. Spanish clinical practice guidelines for the diagnosis and management of cholestatic liver diseases in adult and pediatric population: Joint report from AEEH and SEGHNP.
Authors: Díaz-González Á, Molera C, Gómez-Domínguez E, et al.
Journal: Gastroenterologia y hepatologia, 2026 Apr
PMID: 41232665
DOI: 10.1016/j.gastrohep.2025.502629
2. Efficacy of Advanced Therapies in Achieving Remission by Disease Location in Crohn's Disease: A Systematic Review and Meta-analysis.
Authors: Lee HH, Yuan Y, Boland BS, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Apr
PMID: 40712715
DOI: 10.1016/j.cgh.2025.07.009
3. Chaperonin in health and disease.
Authors: Xu P, Ji M, Zhuang W, et al.
Journal: Molecular biomedicine, 2026 Apr 1
PMID: 41920440
DOI: 10.1186/s43556-026-00437-0
4. The diagnosis and management of portal hypertension in cirrhosis: The Gastroenterological Society of Australia consensus.
Authors: Majumdar A, Holmes J, Roberts SK, et al.
Journal: Hepatology communications, 2026 Apr 1
PMID: 41921189
DOI: 10.1097/HC9.0000000000000934
5. Intestinal Ultrasound for Monitoring Postoperative Crohn's Disease: A Review and Visual Atlas.
Authors: Gu P, Karime C, Fleshner P, et al.
Journal: Inflammatory bowel diseases, 2026 Apr 1
PMID: 41335492
DOI: 10.1093/ibd/izaf248
6. Efficacy and Safety of HSK31679 in Asian Patients With MASLD: A Randomized Controlled Trial.
Authors: Xue F, Ma W, Gao J, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Apr
PMID: 40846146
DOI: 10.1016/j.cgh.2025.08.009
7. Effectiveness and Safety of Orodispersible Budesonide for Eosinophilic Esophagitis: A Multicenter Real-World Study.
Authors: Maniero D, Ghisa M, Bruschi A, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Apr
PMID: 40930303
DOI: 10.1016/j.cgh.2025.08.033
8. Peripancreatic Vascular Involvement and Gastric Varices in Autoimmune Pancreatitis: A Multicenter Retrospective Study.
Authors: Juri N, Masuda A, Nakano R, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Apr
PMID: 40774591
DOI: 10.1016/j.cgh.2025.06.044
9. Advances in Diagnosis and Treatment With Cholangiopancreatoscopy.
Authors: Ogura T, Trong NN, Samanta J
Journal: Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2026 Apr
PMID: 41911952
DOI: 10.1111/den.70141
10. A single-arm phase IIIb study of 8-week glecaprevir/pibrentasvir treatment in adults with acute hepatitis C.
Authors: Llibre JM, Boesecke C, Moon J, et al.
Journal: Journal of hepatology, 2026 Apr
PMID: 41297677
DOI: 10.1016/j.jhep.2025.11.009
Authors: Díaz-González Á, Molera C, Gómez-Domínguez E, et al.
Journal: Gastroenterologia y hepatologia, 2026 Apr
PMID: 41232665
DOI: 10.1016/j.gastrohep.2025.502629
2. Efficacy of Advanced Therapies in Achieving Remission by Disease Location in Crohn's Disease: A Systematic Review and Meta-analysis.
Authors: Lee HH, Yuan Y, Boland BS, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Apr
PMID: 40712715
DOI: 10.1016/j.cgh.2025.07.009
3. Chaperonin in health and disease.
Authors: Xu P, Ji M, Zhuang W, et al.
Journal: Molecular biomedicine, 2026 Apr 1
PMID: 41920440
DOI: 10.1186/s43556-026-00437-0
4. The diagnosis and management of portal hypertension in cirrhosis: The Gastroenterological Society of Australia consensus.
Authors: Majumdar A, Holmes J, Roberts SK, et al.
Journal: Hepatology communications, 2026 Apr 1
PMID: 41921189
DOI: 10.1097/HC9.0000000000000934
5. Intestinal Ultrasound for Monitoring Postoperative Crohn's Disease: A Review and Visual Atlas.
Authors: Gu P, Karime C, Fleshner P, et al.
Journal: Inflammatory bowel diseases, 2026 Apr 1
PMID: 41335492
DOI: 10.1093/ibd/izaf248
6. Efficacy and Safety of HSK31679 in Asian Patients With MASLD: A Randomized Controlled Trial.
Authors: Xue F, Ma W, Gao J, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Apr
PMID: 40846146
DOI: 10.1016/j.cgh.2025.08.009
7. Effectiveness and Safety of Orodispersible Budesonide for Eosinophilic Esophagitis: A Multicenter Real-World Study.
Authors: Maniero D, Ghisa M, Bruschi A, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Apr
PMID: 40930303
DOI: 10.1016/j.cgh.2025.08.033
8. Peripancreatic Vascular Involvement and Gastric Varices in Autoimmune Pancreatitis: A Multicenter Retrospective Study.
Authors: Juri N, Masuda A, Nakano R, et al.
Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2026 Apr
PMID: 40774591
DOI: 10.1016/j.cgh.2025.06.044
9. Advances in Diagnosis and Treatment With Cholangiopancreatoscopy.
Authors: Ogura T, Trong NN, Samanta J
Journal: Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2026 Apr
PMID: 41911952
DOI: 10.1111/den.70141
10. A single-arm phase IIIb study of 8-week glecaprevir/pibrentasvir treatment in adults with acute hepatitis C.
Authors: Llibre JM, Boesecke C, Moon J, et al.
Journal: Journal of hepatology, 2026 Apr
PMID: 41297677
DOI: 10.1016/j.jhep.2025.11.009
